Interactive effects of ovarian steroid hormones on alcohol use and binge drinking across the menstrual cycle.

ABSTRACT: Patterns and features of substance use and abuse vary across the menstrual cycle in humans. Yet, little work has systematically examined the within-person relationships between ovarian hormone changes and alcohol use across the menstrual cycle. Our study was the first to examine the roles of within-person levels of estradiol (E2) and progesterone (P4) in relation to daily alcohol use and binge drinking in young women. Participants were 22 naturally cycling women, ages 18-22, recruited through a university subject pool who reported any alcohol use and who completed a screening visit assessing study eligibility, followed by 35 subsequent days of data collection. E2 and P4 were obtained via enzyme immunoassay of saliva samples collected by participants each morning, 30 min after waking. Prese

SUBMITTER: Martel MM 

PROVIDER: S-EPMC5726306 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature