Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy.

ABSTRACT:

Importance

Maternal antiretroviral treatment (ART) started before conception may increase the risk for adverse birth outcomes among women with human immunodeficiency virus (HIV) infection, but whether the risk differs by ART regimen is unknown.

Objective

To compare the risk for selected birth outcomes by maternal ART regimen.

Design, setting, and participants

This observational birth outcomes surveillance study compared all live births and stillbirths with a gestational age of at least 24 weeks in 8 geographically dispersed government hospitals throughout Botswana (approximately 45% of births nationwide). Data were collected from August 15, 2014, through August 15, 2016.

Exposures

Births among HIV-infected women who started 3-drug ART regimens before their last

SUBMITTER: Zash R 

PROVIDER: S-EPMC5726309 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature