Thin minimal rim width at Bruch's membrane opening is associated with glaucomatous paracentral visual field loss.

ABSTRACT:

Purpose

To compare optic nerve head (ONH) measurements in glaucomatous eyes with paracentral visual field (VF) loss to eyes with peripheral VF loss and controls.

Methods

Open-angle glaucoma (OAG) patients with early paracentral VF loss or isolated peripheral VF loss as well as control subjects underwent ONH imaging with swept-source optical coherence tomography (OCT) and retinal nerve fiber layer (RNFL) imaging with spectral-domain OCT. Minimum rim width at Bruch's membrane opening (BMO-MRW), lamina cribrosa depth (LCD), and RNFL thickness were compared among the glaucoma and control groups with one-way analysis of variance, Kruskal-Wallis test, and multiple regression analysis.

Results

Twenty-nine eyes from 29 OAG patients (15 early paracentral and 14 isolated periph

SUBMITTER: Taniguchi EV 

PROVIDER: S-EPMC5726361 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature