Effects of Prenatal PM₁₀ Exposure on Fetal Cardiovascular Malformations in Fuzhou, China: A Retrospective Case-Control Study.

ABSTRACT:

Background

Maternal exposure to ambient air pollution has been associated with an increased risk of congenital heart defects in offspring; however, the results are inconsistent.

Objectives

We investigated whether there is an association between prenatal exposure to particulate matter with diameter ≤10μm (PM₁₀) during early pregnancy and fetal cardiovascular malformations.

Methods

The gravidae from a hospital-based case–control study in Fuzhou, China, during 2007–2013 were assigned 10-d or 1-mo averages of daily PM₁₀ using an air monitor–based inverse distance weighting method during early pregnancy. A total of 662 live-birth or selectively terminated cases and 3,972 live-birth controls were enrolled. The exposure was considered as a categorical v

SUBMITTER: Liu CB 

PROVIDER: S-EPMC5726369 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature