Genetic variations at 8q24 and gastric cancer susceptibility: A meta-analysis study.

ABSTRACT:

Background

Published data on the association between genetic variants on the 8q24 chromosome and gastric cancer (GC) susceptibility are inconclusive. Here we present a meta-analysis designed to evaluate the relationship between 8q24 variants (single nucleotide polymorphisms (SNPs) labeled rs6983267 and rs1447295) and risk of developing GC.

Methods

A literature search was performed using studies published on PubMed, Science Direct, OVID and Web of Science databases up to December 2016. Studies were selected based on our enrollment criteria, relevant data was extracted from each study and the odds ratios (OR), and 95% confidence intervals (CI) were calculated and used to assess the strength of associations found between 8q24 polymorphisms and GC risk. Conclusions about accepta

SUBMITTER: Zhi P 

PROVIDER: S-EPMC5726661 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature