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Early variations of laboratory parameters predicting shunt-dependent hydrocephalus after subarachnoid hemorrhage.


ABSTRACT:

Background and purpose

Hydrocephalus is a frequent complication following subarachnoid hemorrhage. Few studies investigated the association between laboratory parameters and shunt-dependent hydrocephalus. This study aimed to investigate the variations of laboratory parameters after subarachnoid hemorrhage. We also attempted to identify predictive laboratory parameters for shunt-dependent hydrocephalus.

Methods

Multiple imputation was performed to fill the missing laboratory data using Bayesian methods in SPSS. We used univariate and multivariate Cox regression analyses to calculate hazard ratios for shunt-dependent hydrocephalus based on clinical and laboratory factors. The area under the receiver operating characteristic curve was used to determine the laboratory risk value

SUBMITTER: Na MK 

PROVIDER: S-EPMC5726740 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature