Childhood polybrominated diphenyl ether (PBDE) exposure and executive function in children in the HOME Study.

ABSTRACT: Prenatal exposure to polybrominated diphenyl ethers (PBDEs) have been reported to impair executive function in children, but little is known whether childhood PBDE exposures play a role. Using the Health Outcomes and Measures of the Environment (HOME) Study, a prospective birth cohort in the greater Cincinnati area, we investigated the association between repeated measures of PBDEs during childhood and executive function at 8 years in 208 children and whether effect modification by child sex was present. We used child serum collected at 1, 2, 3, 5, and 8 years to measure PBDEs. The Behavior Rating Inventory of Executive Function was completed by parents to assess executive function at 8 years. We used multiple informant models to examine childhood PBDEs during several exposure windows. Nul

SUBMITTER: Vuong AM 

PROVIDER: S-EPMC5726937 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature