Synergistic Antimicrobial Interaction between Honey and Phage against Escherichia coli Biofilms.

ABSTRACT: Chronic wounds afford a hostile environment of damaged tissues that allow bacterial proliferation and further wound colonization. Escherichia coli is among the most common colonizers of infected wounds and it is a prolific biofilm former. Living in biofilm communities, cells are protected, become more difficult to control and eradicate, and less susceptible to antibiotic therapy. This work presents insights into the proceedings triggering E. coli biofilm control with phage, honey, and their combination, achieved through standard antimicrobial activity assays, zeta potential and flow cytometry studies and further visual insights sought by scanning electron microscopy and transmission electron microscopy. Two Portuguese honeys (PF2 and U3) with different floral origin and an

SUBMITTER: Oliveira A 

PROVIDER: S-EPMC5727068 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature