Admixture mapping of uterine fibroid size and number in African American women.

ABSTRACT:

Objective

To evaluate the relationship between genetic ancestry and uterine fibroid characteristics.

Design

Cross-sectional study.

Setting

Not applicable.

Patient(s)

A total of 609 African American participants with image- or surgery-confirmed fibroids in a biorepository at Vanderbilt University electronic health record biorepository and the Coronary Artery Risk Development in Young Adults studies were included.

Intervention(s)

None.

Main outcome measure(s)

Outcome measures include fibroid number (single vs. multiple), volume of largest fibroid, and largest fibroid dimension of all fibroid measurements.

Result(s)

Global ancestry meta-analyses revealed a significant inverse association between percentage of European ancestry and risk of mult

SUBMITTER: Bray MJ 

PROVIDER: S-EPMC5728674 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature