Performance of the Alere i RSV assay for point-of-care detection of respiratory syncytial virus in children.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) is the most important cause of severe acute respiratory tract infection in young children. Alere i RSV is a novel molecular rapid test which identifies respiratory syncytial virus in less than 13 min.

Methods

We evaluated the clinical performance of the Alere i RSV assay in a pediatric point-of-care setting during winter season 2016 / 2017. Test results from 518 nasopharyngeal swab samples were compared to a real-time reverse transcription PCR reference standard.

Results

The overall sensitivity and specificity of the Alere i RSV test assay was 93% (CI⁹⁵ 89% - 96%) and 96% (CI⁹⁵ 93% - 98%), respectively. Alere i RSV performed well in children of all age groups. An optimal sensitivity of 98% (CI^95</

SUBMITTER: Schnee SV 

PROVIDER: S-EPMC5729395 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature