Deconstructing white matter connectivity of human amygdala nuclei with thalamus and cortex subdivisions in vivo.

ABSTRACT: Structural alterations in long-range amygdala connections are proposed to crucially underlie several neuropsychiatric disorders. While progress has been made in elucidating the function of these connections, our understanding of their structure in humans remains sparse and non-systematic. Harnessing diffusion-weighted imaging and probabilistic tractography in humans, we investigate connections between two main amygdala nucleus groups, thalamic nuclei, and cortex. We first parcellated amygdala into deep (basolateral) and superficial (centrocortical) nucleus groups, and thalamus into six subregions, using previously established protocols based on connectivity. Cortex was parcellated based on T1-weighted images. We found substantial amygdala connections to thalamus, with different patterns fo

SUBMITTER: Abivardi A 

PROVIDER: S-EPMC5729634 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature