Association of neurobehavioral performance with R2* in the caudate nucleus of asymptomatic welders.

ABSTRACT:

Objectives

Welding fumes contain several metals including manganese (Mn) and iron (Fe) that may affect the nervous system. Previous studies of potential welding-related neurotoxicity have focused primarily on Mn exposure. The current study examined neurobehavioral and brain imaging changes in asymptomatic welders and their associations with both Mn and Fe exposure measurements.

Methods

Data were obtained from subjects with (n=46) and without (controls; n=31) a history of welding exposure. Occupational questionnaires estimated recent (HrsW; welding hours and E₉₀; cumulative exposure, past 90days) and lifetime (YrsW; total welding years and ELT; cumulative exposure, lifetime) exposure. Brain MRI pallidal index (PI), R1 (1/T1), and R2* (1/T2*) were measured to estima

SUBMITTER: Lee EY 

PROVIDER: S-EPMC5729887 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature