Physical activity, immune function and inflammation in kidney patients (the PINK study): a feasibility trial protocol.

ABSTRACT:

Introduction

Patients with chronic kidney disease (CKD) display increased infection-related mortality and elevated cardiovascular risk only partly attributed to traditional risk factors. Patients with CKD also exhibit a pro-inflammatory environment and impaired immune function. Aerobic exercise has the potential to positively impact these detriments, but is under-researched in this patient population. This feasibility study will investigate the effects of acute aerobic exercise on inflammation and immune function in patients with CKD to inform the design of larger studies intended to ultimately influence current exercise recommendations.

Methods and analysis

Patients with CKD, including renal transplant recipients, will visit the laboratory on two occasions, both preceded by

SUBMITTER: Highton PJ 

PROVIDER: S-EPMC5729975 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature