Ontology highlight
ABSTRACT:
SUBMITTER: Eisfeld AJ
PROVIDER: S-EPMC5730472 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Cell host & microbe 20171116 6
The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by high levels of virus replication and dissemination, dysregulated immune responses, extensive virus- and host-mediated tissue damage, and disordered coagulation. To clarify how host responses contribute to EVD pathophysiology, we performed multi-platform 'omics analysis of peripheral blood mononuclear cells and plasma from EVD patients. Our results indicate that EVD molecular signatures overlap with those of s ...[more]