High internal noise and poor external noise filtering characterize perception in autism spectrum disorder.

ABSTRACT: An emerging hypothesis postulates that internal noise is a key factor influencing perceptual abilities in autism spectrum disorder (ASD). Given fundamental and inescapable effects of noise on nearly all aspects of neural processing, this could be a critical abnormality with broad implications for perception, behavior, and cognition. However, this proposal has been challenged by both theoretical and empirical studies. A crucial question is whether and how internal noise limits perception in ASD, independently from other sources of perceptual inefficiency, such as the ability to filter out external noise. Here, we separately estimated internal noise and external noise filtering in ASD. In children and adolescents with and without ASD, we computationally modeled individuals' visual orientatio

SUBMITTER: Park WJ 

PROVIDER: S-EPMC5730555 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature