Investigating population continuity with ancient DNA under a spatially explicit simulation framework.

ABSTRACT:

Background

Recent advances in sequencing technologies have allowed for the retrieval of ancient DNA data (aDNA) from skeletal remains, providing direct genetic snapshots from diverse periods of human prehistory. Comparing samples taken in the same region but at different times, hereafter called "serial samples", may indicate whether there is continuity in the peopling history of that area or whether an immigration of a genetically different population has occurred between the two sampling times. However, the exploration of genetic relationships between serial samples generally ignores their geographical locations and the spatiotemporal dynamics of populations. Here, we present a new coalescent-based, spatially explicit modelling approach to investigate population continuity using a

SUBMITTER: Silva NM 

PROVIDER: S-EPMC5731203 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature