Acute kidney injury associated with endurance events-is it a cause for concern? A systematic review.

ABSTRACT:

Introduction

A growing body of evidence suggests even small rises in serum creatinine (SCr) are of considerable clinical relevance. Given that participants in endurance events are exposed to potential (repeated) renal insults, a systematic review was undertaken to collate current evidence for acute kidney injury (AKI), complicating such events.

Methods

A systematic review of studies and case reports meeting inclusion criteria on Medline and EMBASE (inception to October 2015). Included: studies with markers of renal function before and after endurance or ultraendurance events; case reports of severe AKI. Two reviewers assessed risk of bias using the Newcastle-Ottawa scale.

Results

Eleven case report publications (n=27 individuals) of severe AKI, were retrieved, with ri

SUBMITTER: Hodgson LE 

PROVIDER: S-EPMC5731225 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature