Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma.

ABSTRACT: Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide. Due to inadequate screening methods and the common coexistence of limited functional liver reserves, curative treatment options are limited. Liver transplantation is the only curative treatment modality for early HCC. There are multidisciplinary treatment options like ablative treatments, radiation and systemic therapy available for more advanced patients or those that are inoperable. Treatment resistance and progression is inevitable for these HCC patients. Newer therapeutics need to be explored for better management of HCC. HCC is a hypervascular tumor and many pro-angiogenic proteins are found significantly overexpressed in HCC. Here we explored the therapeutic potential of the anti-angiogenic, anti-lymph

SUBMITTER: Barbhuiya MA 

PROVIDER: S-EPMC5731893 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature