Ontology highlight
ABSTRACT:
SUBMITTER: Shi T
PROVIDER: S-EPMC5731921 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Shi Tujin T Quek Sue-Ing SI Gao Yuqian Y Nicora Carrie D CD Nie Song S Fillmore Thomas L TL Liu Tao T Rodland Karin D KD Smith Richard D RD Leach Robin J RJ Thompson Ian M IM Vitello Elizabeth A EA Ellis William J WJ Liu Alvin Y AY Qian Wei-Jun WJ
Oncotarget 20171009 60
Biomarkers for effective early diagnosis and prognosis of prostate cancer are still lacking. Multiplexed assays for cancer-associated proteins could be useful for identifying biomarkers for cancer detection and stratification. Herein, we report the development of sensitive targeted mass spectrometry assays for simultaneous quantification of 10 prostate cancer-associated proteins in urine. The diagnostic utility of these markers was evaluated with an initial cohort of 20 clinical urine samples. I ...[more]