Blood transfusion and mortality in myocardial infarction: an updated meta-analysis.

ABSTRACT:

Background

Several observational and preclinical studies have shown that blood transfusion may modify the mortality of patients with myocardial infarction (MI). The aim of this meta-analysis is to evaluate the recent evidence on the effectiveness of blood transfusion for all-cause mortality in patients with MI.

Materials and methods

PUBMED, EMBASE and the Cochrane central register of controlled trials were searched up to June 2016 by two independent investigators. Studies were considered eligible if they recruited adult MI patients and reported hazard ratio (HR) for all-cause mortality comparing those who received blood transfusion with those who did not receive blood transfusion. We abstracted and calculated pooled HRs using a random-effects model.

Results

From 4277

SUBMITTER: Yin Z 

PROVIDER: S-EPMC5731951 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature