Development of a Rapid Salivary Proteomic Platform for Oral Feeding Readiness in the Preterm Newborn.

ABSTRACT: Oral feeding competency is a major determinant of length of stay in the neonatal intensive care unit. An infant must be able to consistently demonstrate the ability to take all required enteral nutrition by mouth before discharge home. Most infants born prematurely (<37 weeks) will require days, if not weeks, to master this oral feeding competency skill. Inappropriately timed feeding attempts can lead to acute and long-term morbidities, prolonged hospitalizations, and increased health-care costs. Previously, a panel of five genes involved in essential developmental pathways including sensory integration (nephronophthisis 4, Plexin A1), hunger signaling [neuropeptide Y2 receptor (NPY2R), adenosine-monophosphate-activated protein kinase (AMPK)], and facial

SUBMITTER: Khanna P 

PROVIDER: S-EPMC5733069 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature