Tetrad analysis in plants and fungi finds large differences in gene conversion rates but no GC bias.

ABSTRACT: GC-favouring gene conversion enables fixation of deleterious alleles, disturbs tests of natural selection and potentially explains both the evolution of recombination as well as the commonly reported intragenomic correlation between G+C content and recombination rate. In addition, gene conversion disturbs linkage disequilibrium, potentially affecting the ability to detect causative variants. However, the importance and generality of these effects is unresolved, not simply because direct analyses are technically challenging but also because previous within- and between-species discrepant results can be hard to appraise owing to methodological differences. Here we report results of methodologically uniform whole-genome sequencing of all tetrad products in Saccharomyces, Neurospora, Chlamydom

SUBMITTER: Liu H 

PROVIDER: S-EPMC5733138 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature