Identification of pterygium-related mRNA expression profiling by microarray analysis.

ABSTRACT: PurposePterygium is a common degenerative and proliferative disease of the ocular surface. In some severe cases, pterygium may lead to irregular corneal astigmatism and corneal stromal scarring with visual impairment. The proliferative capacities of pterygial cells make them appear similar to tumorigenesis. Although considerable progress has been made towards understanding the etiology of the disease, the pathogenesis of pterygium has not been completely understood. In our previous study, we constructed pterygium-related lncRNA libraries by using microarray to investigate the potential roles of lncRNAs in pterygium. In this study, our objective was to explore the role of mRNA in pterygium.Patients and methodsIn this study, we constructed pterygium-related mRNA libraries by using microarray

SUBMITTER: Liu J 

PROVIDER: S-EPMC5733281 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature