Variation in the Sweet Taste Receptor Gene and Dietary Intake in a Swedish Middle-Aged Population.

ABSTRACT:

Background

The preference for sweet taste is partially genetically determined. The major allele of the single nucleotide polymorphism rs12033832 in the sweet taste receptor (TAS1R2) has previously been associated with lower sugar sensitivity and higher sugar intake among overweight individuals. The aim of the present study was to examine the association between dietary intake and the TAS1R2 genotype in lean and overweight individuals in the population-based Malmö Diet and Cancer (MDC) cohort using dietary intake data with a high validity.

Methods

In total, 3,602 participants (46-68 years old) from the MDC cohort who underwent baseline examinations between 1991 and 1994, who were non-smokers without diabetes, and for whom information regarding TAS1R2 rs75

SUBMITTER: Habberstad C 

PROVIDER: S-EPMC5733356 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature