Lupus Nephritis in Males: Clinical Features, Course, and Prognostic Factors for End-Stage Renal Disease.

ABSTRACT:

Introduction

Because of their rarity in men, systemic lupus erythematous and lupus nephritis (LN) are poorly understood in men. Our aim was to analyze the clinical presentation and course of histology-proven systemic lupus erythematous and LN in males and to determine the risk factors for progression to end-stage renal disease.

Methods

Fifty patients from 2 historical cohorts in Spain (Hospital 12 de Octubre) and Uruguay were retrospectively analyzed and compared with a female cohort matched for age and disease characteristics.

Results

The median age at the time of renal biopsy was 27 years (range, 8-79 years). The main forms of presentation were nephrotic syndrome in 26 of 50 patients (52%), and class IV LN in 34 of 50 (68%). After treatment, 21 patients (45.6%) achi

SUBMITTER: Urrestarazu A 

PROVIDER: S-EPMC5733876 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature