A cross-sectional study measuring vanadium and chromium levels in paediatric patients with CKD.

ABSTRACT:

Objectives

Although many secondary effects of high levels of vanadium (V) and chromium (Cr) overlap with symptoms seen in paediatric patients with chronic kidney disease (CKD), their plasma V and Cr levels are understudied.

Design

Ancillary cross-sectional study to a prospective, longitudinal, randomised controlled trial.

Setting

Children's Hospital of Western Ontario, London Health Sciences Centre, London, Ontario, Canada.

Participants

36 children and adolescents 4-18 years of age with CKD.

Interventions

1-6 trace element measurements per patient. Cystatin C (CysC) estimated glomerular filtration rate (eGFR) was calculated using the Filler formula. Plasma V and Cr levels were measured using high-resolution sector field inductively coupled mass spectrome

SUBMITTER: Filler G 

PROVIDER: S-EPMC5734203 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature