Bacterial meningitis in Finland, 1995-2014: a population-based observational study.

ABSTRACT:

Objectives

Bacterial meningitis remains an important cause of morbidity and mortality worldwide. Its epidemiological characteristics, however, are changing due to new vaccines and secular trends. Conjugate vaccines against Haemophilus influenzae type b and Streptococcus pneumoniae (10-valent) were introduced in 1986 and 2010 in Finland. We assessed the disease burden and long-term trends of five common causes of bacterial meningitis in a population-based observational study.

Methods

A case was defined as isolation of S. pneumoniae, Neisseria meningitidis, Streptococcus agalactiae, Listeria monocytogenes or H. influenzae from cerebrospinal fluid and reported to national, population-based laboratory surveillance system during 19

SUBMITTER: Polkowska A 

PROVIDER: S-EPMC5734207 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature