Serum fibrinogen and cardiovascular events in Chinese patients with type 2 diabetes and stable coronary artery disease: a prospective observational study.

ABSTRACT:

Objectives

The aim of this study was to investigate the association of serum fibrinogen with cardiovascular events (CVE) in Chinese patients with type 2 diabetes mellitus (T2DM) and stable coronary artery disease (CAD).

Design

An observational study.

Setting

FuWai Hospital in Beijing, China.

Participants

A cohort of 1466 patients with T2DM and angiographic-proven stable CAD was evaluated.

Outcome measures

Baseline serum fibrinogen levels were measured and trisected into 'low', 'middle' and 'high'. Their association with CVE was explored using Cox proportional hazard models.

Results

With 20.2 months (average) follow-up, 44 (3%) were lost to follow-up and 96 patients developed CVE. Compared with the patients without CVE, the ones who developed CVE h

SUBMITTER: Yang SH 

PROVIDER: S-EPMC5734258 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature