Transcatheter closure, mini-invasive closure and open-heart surgical repair for treatment of perimembranous ventricular septal defects in children: a protocol for a network meta-analysis.

ABSTRACT:

Introduction

Both transcatheter device closure and surgical repair are effective treatments with excellent midterm outcomes for perimembranous ventricular septal defects (pmVSDs) in children. The mini-invasive periventricular device occlusion technique has become prevalent in research and application, but evidence is limited for the assessment of transcatheter closure, mini-invasive closure and open-heart surgical repair. This study comprehensively compares the efficacy, safety and costs of transcatheter closure, mini-invasive closure and open-heart surgical repair for treatment of pmVSDs in children using Bayesian network meta-analysis.

Methods and analysis

A systematic search will be performed using Chinese Biomedical Literature Database, China National Knowledge Infrastru

SUBMITTER: You T 

PROVIDER: S-EPMC5734259 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature