Non-withdrawal of beta blockers in acute decompensated chronic and de novo heart failure with reduced ejection fraction in a prospective multicentre study of patients with acute heart failure in the Middle East.

ABSTRACT:

Objectives

Beta blockers reduce mortality in heart failure (HF). However, it is not clear whether they should be temporarily withdrawn during acute HF.

Design

Analysis of prospectively collected data.

Setting

The Gulf aCute heArt failuRe rEgistry is a prospective multicentre study of patients hospitalised with acute HF in seven Middle Eastern countries.

Participants

5005 patients with acute HF.

Outcome measures

We studied the effect of beta blockers non-withdrawal on intrahospital, 3-month and 12-month mortality and rehospitalisation for HF in patients with acute decompensated chronic heart failure (ADCHF) and acute de novo heart failure (ADNHF) and a left ventricular ejection fraction (LVEF) <40%.

Results

44.1% of patients were already on beta bl

SUBMITTER: Abi Khalil C 

PROVIDER: S-EPMC5734353 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature