Sleep-wake functions and quality of life in patients with subthalamic deep brain stimulation for Parkinson's disease.

ABSTRACT:

Objectives

Sleep-wake disturbances (SWD) are frequent in Parkinson's disease (PD). The effect of deep brain stimulation (DBS) on SWD is poorly known. In this study we examined the subjective and objective sleep-wake profile and the quality of life (QoL) of PD patients in the context of subthalamic DBS.

Patients and methods

We retrospectively analyzed data from PD patients and candidates for DBS in the nucleus suthalamicus (STN). Pre-DBS, sleep-wake assessments included subjective and objective (polysomnography, vigilance tests and actigraphy) measures. Post-DBS, subjective measures were collected. QoL was assessed using the Parkinson's Disease Questionnaire (PDQ-39) and the RAND SF-36-item Health Survey (RAND SF-36).

Results

Data from 74 PD patients (62% male, mean ag

SUBMITTER: Bargiotas P 

PROVIDER: S-EPMC5734707 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature