Evidence for causal top-down frontal contributions to predictive processes in speech perception.

ABSTRACT: Perception relies on the integration of sensory information and prior expectations. Here we show that selective neurodegeneration of human frontal speech regions results in delayed reconciliation of predictions in temporal cortex. These temporal regions were not atrophic, displayed normal evoked magnetic and electrical power, and preserved neural sensitivity to manipulations of sensory detail. Frontal neurodegeneration does not prevent the perceptual effects of contextual information; instead, prior expectations are applied inflexibly. The precision of predictions correlates with beta power, in line with theoretical models of the neural instantiation of predictive coding. Fronto-temporal interactions are enhanced while participants reconcile prior predictions with degraded sensory signals.

SUBMITTER: Cope TE 

PROVIDER: S-EPMC5735133 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature