Medical therapies for heavy menstrual bleeding in women with uterine fibroids: a retrospective analysis of a large commercially insured population in the USA.

ABSTRACT:

Objectives

To report patterns and patient characteristics associated with initiation of and persistence with medical therapies for uterine fibroid-related heavy menstrual bleeding.

Design

Retrospective cohort study.

Setting

US commercial insurance claims database.

Population

41 561 women aged 18-54 years with uterine fibroids and heavy menstrual bleeding who initiated medical therapies from January 2000 through December 2013.

Method

Multinomial logistic regression was used to assess patient characteristics associated with initiation and persistence. Cox proportional hazards regression was used on propensity score-matched cohorts to examine change from index medication.

Main outcomes measures

Initiation of and persistence with four first-line medic

SUBMITTER: Yao X 

PROVIDER: S-EPMC5736004 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature