Ambulatory versus inpatient management of severe nausea and vomiting of pregnancy: a randomised control trial with patient preference arm.

ABSTRACT:

Objective

To determine whether ambulatory (outpatient (OP)) treatment of severe nausea and vomiting of pregnancy (NVP) is as effective as inpatient (IP) care.

Design

Non-blinded randomised control trial (RCT) with patient preference arm.

Setting

Two multicentre teaching hospitals in London.

Participants

Women less than 20 weeks' pregnant with severe NVP and associated ketonuria (>1+).

Methods

Women who agreed to the RCT were randomised via web-based application to either ambulatory or IP treatment. Women who declined randomisation underwent the treatment of their choice in the patient preference trial (PPT) arm. Treatment protocols, data collection and follow-up were the same for all participants.

Main outcome measures

Primary outcome was reductio

SUBMITTER: Mitchell-Jones N 

PROVIDER: S-EPMC5736029 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature