Comparison of enteral versus intravenous potassium supplementation in hypokalaemia in paediatric patients in intensive care post cardiac surgery: open-label randomised equivalence trial (EIPS).

ABSTRACT:

Objectives

The primary objective was to compare the efficacy of enteral potassium replacement (EPR) and intravenous potassium replacement (IVPR) as first-line therapy. Secondary objectives included comparison of adverse effects and number of doses required to resolve the episode of hypokalaemia.

Trial design

The EIPS trial is designed as a randomised, equivalence trial between two treatment arms.

Study setting

The study was conducted at the paediatric cardiac intensive care unit (PCICU) at Aga Khan University Hospital, Karachi.

Participants

41 patients (aged 1 month to 15 years) who were admitted to PCICU post cardiac surgery were recruited (23 IVPR arm and 18 EPR arm).

Intervention

Intervention arms were block randomised on alternate weeks for IVPR and

SUBMITTER: Rehman Siddiqu NU 

PROVIDER: S-EPMC5736091 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature