Statin use is associated with improved survival in ovarian cancer: A retrospective population-based study.

ABSTRACT:

Background

Preclinical in vitro and in vivo studies suggest that statins could exhibit anticancer properties in ovarian cancer. Similar effects have also been reported in observational studies but their results remain inconsistent and could be impaired by methodological limitations. This study aimed to investigate whether statin use is associated with improved survival in ovarian cancer patients at the Belgian population-level.

Methods

All patients with invasive epithelial ovarian cancer diagnosed between 2004 and 2012 were identified from the Belgian Cancer Registry. Vital statuses were obtained from the Crossroads Bank for Social Security and ovarian cancer-specific deaths were identified from death certificates provided by regional administrations. Information on cancer t

SUBMITTER: Couttenier A 

PROVIDER: S-EPMC5736195 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature