Large coverage black-bright blood interleaved imaging sequence (LaBBI) for 3D dynamic contrast-enhanced MRI of vessel wall.

ABSTRACT:

Purpose

To propose a large coverage black-bright blood interleaved imaging sequence (LaBBI) for 3D dynamic contrast-enhanced MRI (DCE-MRI) of the vessel wall.

Methods

LaBBI consists of a 3D black-blood stack-of-stars golden angle radial acquisition with high spatial resolution for vessel wall imaging and a 2D bright-blood Cartesian acquisition with high temporal resolution for arterial input function estimation. The two acquisitions were performed in an interleaved fashion within a single scan. Simulations, phantom experiments, and in vivo tests in three patients were performed to investigate the feasibility and performance of the proposed LaBBI.

Results

In simulation tests, the estimated K^trans and v_p by LaBBI were more accurate than conventiona

SUBMITTER: Qi H 

PROVIDER: S-EPMC5736472 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature