Effect of involved Aspergillus species on galactomannan in bronchoalveolar lavage of patients with invasive aspergillosis.

ABSTRACT:

Purpose

The detection of galactomannan (GM) in bronchoalveolar lavage (BAL) fluid is an important surrogate marker for the early diagnosis and therapeutic monitoring of invasive aspergillosis (IA), regardless of the involved species of Aspergillus. Here, we utilized the Platelia Aspergillus GM enzyme immunoassay (Bio-Rad) to evaluate the GM index in BAL fluid samples from patients with proven, probable or putative IA due to Aspergillusflavus versus Aspergillusfumigatus.

Methodology

In a prospective study between 2009 and 2015, 116 BAL samples were collected from suspected IA patients referred to two university hospitals in Tehran, Iran.

Key findings

According to European Organization for Research and Treatment of Cancer and Mycoses Study Group and Blot criteria, 35 pa

SUBMITTER: Taghizadeh-Armaki M 

PROVIDER: S-EPMC5737110 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature