Task-Related Functional Connectivity Analysis of Emotion Discrimination in a Family Study of Schizophrenia.

ABSTRACT: Poor emotion recognition is a core deficit in schizophrenia and is associated with poor functional outcome. Functional magnetic resonance imaging (fMRI) multivariate analysis methods were used to elucidate the neural underpinnings of face and emotion processing associated with both genetic liability and disease-specific effects. Schizophrenia patients, relatives, and controls completed a task that included 4 facial emotion discrimination conditions and an age discrimination condition during fMRI. Three functional networks were derived from the data: the first involved in visual attention and response generation, the second a default mode network (DMN), and a third involved in face and emotion processing. No differences in activation were found between groups for the visual attention and re

SUBMITTER: Goghari VM 

PROVIDER: S-EPMC5737224 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature