Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.

ABSTRACT:

Background

Brain metastases are associated with significant morbidity and mortality. Population-level data describing the incidence and prognosis of patients with brain metastases are lacking. The aim of this study was to characterize the incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy using recently released data from the Surveillance, Epidemiology, and End Results (SEER) program.

Methods

We identified 1302166 patients with diagnoses of nonhematologic malignancies originating outside of the CNS between 2010 and 2013 and described the incidence proportion and survival of patients with brain metastases.

Results

We identified 26430 patients with brain metastases at diagnosis of cancer. Patients with small cell and non-small

SUBMITTER: Cagney DN 

PROVIDER: S-EPMC5737512 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature