Tsetse fly (Glossina pallidipes) midgut responses to Trypanosoma brucei challenge.

ABSTRACT:

Background

Tsetse flies (Glossina spp.) are the prominent vector of African trypanosome parasites (Trypanosoma spp.) in sub-Saharan Africa, and Glossina pallidipes is the most widely distributed species in Kenya. This species displays strong resistance to infection by parasites, which are typically eliminated in the midgut shortly after acquisition from the mammalian host. Although extensive molecular information on immunity for the related species Glossina morsitans morsitans exists, similar information is scarce for G. pallidipes.

Methods

To determine temporal transcriptional responses of G. pallidipes to Trypanosoma brucei brucei challenge, we conducted Illumina based RNA-seq on midgut organ and carcass from teneral females G. pallidipes at 24 and 48 h post-challenge (hpc

SUBMITTER: Bateta R 

PROVIDER: S-EPMC5738168 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature