Heartbeat Complexity Modulation in Bipolar Disorder during Daytime and Nighttime.

ABSTRACT: This study reports on the complexity modulation of heartbeat dynamics in patients affected by bipolar disorder. In particular, a multiscale entropy analysis was applied to the R-R interval series, that were derived from electrocardiographic (ECG) signals for a group of nineteen subjects comprised of eight patients and eleven healthy control subjects. They were monitored using a textile-based sensorized t-shirt during the day and overnight for a total of 47 diurnal and 27 nocturnal recordings. Patients showed three different mood states: depression, hypomania and euthymia. Results show a clear loss of complexity during depressive and hypomanic states as compared to euthymic and healthy control states. In addition, we observed that a more significant complexity modulation among healthy and p

SUBMITTER: Nardelli M 

PROVIDER: S-EPMC5738374 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature