Risk of Cardiovascular Events in Patients With Diabetes Mellitus on β-Blockers.

ABSTRACT: Although the use of β-blockers may help in achieving maximum effects of intensive glycemic control because of a decrease in the adverse effects after severe hypoglycemia, they pose a potential risk for the occurrence of severe hypoglycemia. This study aimed to evaluate whether the use of β-blockers is effective in patients with diabetes mellitus and whether its use is associated with the occurrence of severe hypoglycemia. Using the ACCORD trial (Action to Control Cardiovascular Risk in Diabetes) data, we performed Cox proportional hazards analyses with a propensity score adjustment. The primary outcome was the first occurrence of a cardiovascular event during the study period, which included nonfatal myocardial infarction, unstable angina, nonfatal stroke, and cardiovascular death. The mea

SUBMITTER: Tsujimoto T 

PROVIDER: S-EPMC5739105 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature