The Antimetastatic and Antiangiogenesis Effects of Kefir Water on Murine Breast Cancer Cells.

ABSTRACT:

Background

Kefir is a unique cultured product that contains beneficial probiotics. Kefir culture from other parts of the world exhibits numerous beneficial qualities such as anti-inflammatory, immunomodulation, and anticancer effects. Nevertheless, kefir cultures from different parts of the world exert different effects because of variation in culture conditions and media. Breast cancer is the leading cancer in women, and metastasis is the major cause of death associated with breast cancer. The antimetastatic and antiangiogenic effects of kefir water made from kefir grains cultured in Malaysia were studied in 4T1 breast cancer cells.

Methods

4T1 cancer cells were treated with kefir water in vitro to assess its antimigration and anti-invasion effects. BALB/c mice were injecte

SUBMITTER: Zamberi NR 

PROVIDER: S-EPMC5739168 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature