Clinical predictors of outcome in patients with inflammatory dilated cardiomyopathy.

ABSTRACT:

Objectives

The study objectives were to identify predictors of outcome in patients with inflammatory dilated cardiomyopathy (DCMi).

Methods

From 2004 to 2008, 55 patients with biopsy-proven DCMi were identified and followed up for 58.2±19.8 months. Predictors of outcome were identified in a multivariable analysis with a Cox proportional hazards analysis. The primary endpoint was a composite of death, heart transplantation and hospitalization for heart failure or ventricular arrhythmias.

Results

For the primary endpoint, a QTc interval >440msec (HR 2.84; 95% CI 1.03-7.87; p = 0.044), a glomerular filtration rate (GFR) <60ml/min/1.73m2 (HR 3.19; 95% CI 1.35-7.51; p = 0.008) and worsening of NYHA classification during follow-up (HR 2.48; 95% CI 1.01-6.10; p = 0.048) were

SUBMITTER: Karatolios K 

PROVIDER: S-EPMC5739391 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature