Equivalent linear change in cognition between individuals with bipolar disorder and healthy controls over 5 years.

ABSTRACT:

Objectives

Cognitive dysfunction is a key feature of bipolar disorder (BD). However, not much is known about its temporal stability, as some studies have demonstrated a neurodegenerative model in BD while others have shown no change in cognitive functioning over time. Building upon our prior work, which examined the natural course of executive functioning, the current study aimed to investigate the natural course of memory, emotion processing, and fine motor dexterity over a 5-year period in BD and healthy control (HC) samples.

Methods

Using a 5-year longitudinal cohort, 90 individuals with BD and 17 HCs were administered a battery of neuropsychological tests at study baseline and at 1 and 5 years after study entry that captured four areas of cognitive performance: visual me

SUBMITTER: Ryan KA 

PROVIDER: S-EPMC5740000 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature