From network to phenotype: the dynamic wiring of an Arabidopsis transcriptional network induced by osmotic stress.

ABSTRACT: Plants have established different mechanisms to cope with environmental fluctuations and accordingly fine-tune their growth and development through the regulation of complex molecular networks. It is largely unknown how the network architectures change and what the key regulators in stress responses and plant growth are. Here, we investigated a complex, highly interconnected network of 20 Arabidopsis transcription factors (TFs) at the basis of leaf growth inhibition upon mild osmotic stress. We tracked the dynamic behavior of the stress-responsive TFs over time, showing the rapid induction following stress treatment, specifically in growing leaves. The connections between the TFs were uncovered using inducible overexpression lines and were validated with transient expression assays. This s

SUBMITTER: Van den Broeck L 

PROVIDER: S-EPMC5740496 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature