Convergent origination of a <i>Drosophila</i>-like dosage compensation mechanism in a reptile lineage.

ABSTRACT: Sex chromosomes differentiated from different ancestral autosomes in various vertebrate lineages. Here, we trace the functional evolution of the XY Chromosomes of the green anole lizard (Anolis carolinensis), on the basis of extensive high-throughput genome, transcriptome and histone modification sequencing data and revisit dosage compensation evolution in representative mammals and birds with substantial new expression data. Our analyses show that Anolis sex chromosomes represent an ancient XY system that originated at least ≈160 million years ago in the ancestor of Iguania lizards, shortly after the separation from the snake lineage. The age of this system approximately coincides with the ages of the avian and two mammalian sex chromosomes systems. To compensate for the alm

SUBMITTER: Marin R 

PROVIDER: S-EPMC5741051 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature