Prediction of Type 2 Diabetes by Hemoglobin A_1c in Two Community-Based Cohorts.

ABSTRACT:

Objective

Hemoglobin A_1c (HbA_1c) can be used to assess type 2 diabetes (T2D) risk. We asked whether HbA_1c was associated with T2D risk in four scenarios of clinical information availability: 1) HbA_1c alone, 2) fasting laboratory tests, 3) clinic data, and 4) fasting laboratory tests and clinic data.

Research design and methods

We studied a prospective cohort of white (N = 11,244) and black (N = 2,294) middle-aged participants without diabetes in the Framingham Heart Study and Atherosclerosis Risk in Communities study. Association of HbA_1c with incident T2D (defined by medication use or fasting glucose [FG] ≥126 mg/dL) was evaluated in regression models adjusted for 1) age

SUBMITTER: Leong A 

PROVIDER: S-EPMC5741154 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature