High hemoglobin A_1c associated with increased adverse limb events in peripheral arterial disease patients undergoing revascularization.

ABSTRACT:

Objective

Diabetes and peripheral arterial disease (PAD) are independently associated with increased risk of amputation. However, the effect of poor glycemic control on adverse limb events has not been studied. We examined the effects of poor glycemic control (high hemoglobin A_1c level) on the risk of amputation and modified major adverse limb events (mMALEs) after lower extremity revascularization.

Methods

Patients undergoing PAD revascularization who had hemoglobin A_1c (HbA_1c) levels available within 6 months were identified in the Veterans Affairs database of 2003 to 2014 (N = 26,799). The diagnosis of preoperative diabetes mellitus (PreopDM) was defined using diabetes diagnosis codes and evidence of treatment. Amputation and mMALE risk wa

SUBMITTER: Arya S 

PROVIDER: S-EPMC5741490 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature